The gut distinguishes sugar from low-calorie sweeteners, and tells the brain what has been eaten within milliseconds, studies in mice and human cells suggest
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https://www.newscientist.com/article/2237893-our-guts-may-sense-sugar-and-low-calorie-sweeteners-differently/?utm_campaign=RSS%7CNSNS&utm_source=NSNS&utm_medium=RSS&utm_content=home
